Management of severe Stevens–Johnson syndrome

Background Severe exfoliative diseases of the skin (Erythema multiforme, Stevens–Johnson syndrome SJS, toxic epidermal necrolysis -TEN) are a result of an immunological reaction to foreign antigens, most frequently caused by drug consumption. It is characterized by extensive damage to the skin and mucous membranes due to detachment at the dermoepidermal junction, very similar to post-combustional lesions. This article wants to emphasize on the role of the plastic surgeon in the management of exfoliative diseases of the skin and the reason why patients suffering from SJS or TEN should be directed and treated in burn intensive care units, where they can receive adequate fluid resuscitation, nutritional support, wound care and physical therapy.